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Intestinal VDR knockout protected against oxazolone-induced colitis in mice by blocking Th2 cell response and reducing the function of abdominal iNKT cells. Vitamin D status had no impact on the seriousness of colitis. This research may give an explanation for diverse effects after supplement D supplementation in literary works and add some clue to the specific treatment of IBD.Early life exposures are essential predictors of person condition threat. Although the fundame