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Conclusions . This study confirms the security of frozen intravitreal topotecan syringes and will help optimize the usage this chemotherapy modality at organizations with low resources. Storing of aliquots may also reduce personnel experience of chemotherapy at hospital pharmacies.Background Studies advise organizations between gas and oil development (OGD) and adverse birth results, but few epidemiological researches of oil wells or sedentary wells exist, and nothing in California. Unbiased Our research