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The elimination half-life of vancomycin decreased from 64.1±35.7h before SLEDD-f to 7.0±3.0h during SLEDD-f. Significant amount of vancomycin removed during SLEDD-f. Despite the existence of post-dialysis rebound, a sufficient supplemental dose is necessary to maintain therapeutic range. Significant amount of vancomycin removed during SLEDD-f. Despite the existence of post-dialysis rebound, a sufficient supplemental dose is necessary to maintain therapeutic range. To update information about the internationally accepted standards and cl