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In this review, we highlight the part of this axis in modulating enteric and central nervous system function and exactly how this could influence disorders such as for example irritable bowel problem and conditions of feeling and impact. We analyze the overlapping biological constructs that underpin these conditions with a unique emphasis on the neurotransmitter serotonin, which plays an integral part both in the gastrointestinal tract as well as in the brain. Overall, its clear that although ani