https://www.selleckchem.com/products/gdc-0068.html
In this chapter, the interaction between metabolic driven changes of transcriptional programs in the context of tumorigenesis will be discussed.Cutaneous melanoma is one of the most aggressive types of cancer, presenting the highest potential to form metastases, both locally and distally, which are associated with high death rates of melanoma patients. A high somatic mutation burden is characteristic of these tumours, with most common oncogenic mutations occurring in the BRAF, NRAS and NF1 genes. These intrinsic oncogenic pathways cont
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