Causes of Truck Crash Accidents If a truck crashes, the driver may be at fault, but there are many other factors that could contribute to an accident. of the most common causes include driver fatigue, Impaired driving, and the fact that a truck is loaded with hazardous cargo. The companies that make these equipment could be accountable for any damage. If you suffer injuries, you should seek medical assistance as soon as you can. Document evidence of the crash and share information with the other party. Take a copy police report. Also, keep a