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In laser ablation inductively coupled plasma size spectrometry (LA-ICP-MS) analysis, it really is challenging to quantitatively analyse a low amount of titanium concentration. Two methods had been employed utilizing a quadrupole mass spectrometer built with a collision/reaction cell (CRC). In the 1st method, the MS/MS mass-shift mode with oxygen effect gas provided reliable and consistent dimension of titanium as 48Ti16O+. Within the second method, the t