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The Co-NC possessed the adsorption capability for small molecular compounds, also it ended up being believed that the adsorption capability of Co-NC might split up the analytes from the sodium in microdialysates at a microscopic amount, which might facilitate the desorption and ionization for the analytes and lastly enhanced the salt-tolerance ability as a matrix. Moreover, the Co-NC-assisted LDI ion origin as a novel screen of in vivo microdialysis coupled with MS is put o
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