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Introduction There were few data about the clinical profiles and long-term outcomes in Chinese patients with atrial fibrillation (AF) and bioprosthetic valves. Methods The retrospective study enrolled 903 patients with bioprosthetic valve replacement at our hospital and discharged with a diagnosis of AF from January 2010 to December 2018. Results The median age was 65.6 (61.9-69.1) years, and 548 (60.7%) patients were women. During a follow-up period of 3.84 (2.64-5.51) years, 68 (1.8 per 100 person-years) patients died, 81 (2.1 per 100