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Between April and November 2019, 286 successive patients undergoing TAVR utilizing the LOTUS Edge system at 18 European centers were included. The mean age and culture of Thoracic Surgeons score had been 81.2 ± 6.9 years and 5.2 ± 5.4%, correspondingly. Almost one-half of all patients (47.9%) had been thought to have complex structure. Thirty-day major negative events itudy will evaluate if increasing operator experience with the device and brand-new implantation strategy decrease the occurrence of