https://smadsignaling.com/pred....ictability-associate
Hence, key concerns towards eradication of HIV infection are to know the systems that enable HIV latency and to develop latency reversal agents (LRAs) that will facilitate the clearance of latently infected cells. The repressive H3K27me3 histone mark, catalyzed by the PRC2 complex, plays a pivotal part in transcriptional repression during the viral promoter in both cellular line and primary CD4+ T cell models of latency. EZH2 inhibitors which block H3K27 methy
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