https://bcl6signaling.com/inde....x.php/pfk-initial-is
Recently, it had been stated that mHTT is present into the intermembrane room and prevents mitochondrial protein import by reaching TIM23, an important part of mitochondrial protein import machinery, but proof for functional implications were not provided. We assessed mHTT location using synaptic and nonsynaptic mitochondria isolated from brains of YAC128 mice and afflicted by alkali therapy or limited trypsin food digestion. Mitochondria were purified either with discont
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