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Lithium regulates SOCE; however, whether therapeutic levels of lithium may be used to inhibit cardiac fibrogenesis is unidentified. Migration and proliferation assays, Western blotting, real time reverse-transcription polymerase string reaction evaluation, and calcium fluorescence imaging were done in man cardiac fibroblasts treated with or without LiCl at 1.0 mM (for example., therapeutic top degree) or 0.1 mM (in other words., therapeutic trough l