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mune system has been detected by suppressed mHLA-DR levels, the immune system can be safely reactivated by IFNγ. After a compromised immune system has been detected by suppressed mHLA-DR levels, the immune system can be safely reactivated by IFNγ. Leishmaniasis is a neglected arthropod-borne disease that affects millions of people worldwide. Successful infections require the mitigation of immune cell functions leading to parasite survival and proliferation. A large body of evidence highlights the involvement of neutrophils (PMNs) and de