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This analysis aims to present a novel approach of tumour detection, contouring and targeted radiotherapy of HNCs using visualisation of CAFs PET-CT with 68Ga-radiolabeled inhibitors of FAP (FAPI). Methods FAPI PET-CT was performed without problems prior to radiotherapy along with contrast improved CT (CE-CT) and MRI on 14 customers with HNC. Initially, for tissue biodistribution evaluation, amounts of interest were defined to quantify SUVmean and SUVmax in tumour and healthy parenchyma. Subsequentl