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Clickable MBCs were synthesized by changing the structure of the nucleophile to obtain degradable amphiphilic conetworks and hydrogels. Varieties of macromolecular entities could be obtained by switching the nucleophilic agent and introducing a small molecular weight chain extender. This synthesis approach provides an opportunity to tune the chemical functionality, topological structure, and biological properties of macromolecular entities.Amyloid beta (Aβ) peptides are notorious for their involvement in Alzheimer's disease (AD), by vir
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