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To analyze the Quality of Life at Work (QOL) of dentists in Antioquia, Colombia, based on objective and subjective components. A sample of 323 dentists was used for a descriptive study using a structured survey. Data were processed using in SPSS 17.0 and Epidat 3.1 software. Significant trends (p0.05) were found for the decrease of male, home-based and postgraduate professionals. Fewer and fewer professionals earn more than five times the legal monthly minimum wage, have access to private health services, and enjoy more than