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Online Social Network (OSN) is considered a key source of information for real-time decision making. However, several constraints lead to decreasing the amount of information that a researcher can have while increasing the time of social network mining procedures. In this context, this paper proposes a new framework for sampling Online Social Network (OSN). Domain knowledge is used to define tailored strategies that can decrease the budget and time required for mining while increasing the recall. An ontology supports our filtering layer in evaluating the re