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Modeling efforts could help predict case scenarios and select a proper design and approach, while BES-based biosensing could help monitoring remediation processes. In this review, we critically analyze in situ BES applications for groundwater remediation, focusing in particular on different proposed setups, and we identify and discuss the existing research gaps in the field. Biological desulfurization technology is a sustainable process for the sulfide removal from biogas, which has multiple advantages. In this study, a biological sulfide