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73 cases/100 days of treatment (prevalence of 15.56%). Colistin nephrotoxicity has an important incidence, without developing severe illness. Colistin nephrotoxicity has an important incidence, without developing severe illness.Adults aged 65 years or older suffer the most severe health effects of seasonal flu. Although the influenza vaccine is effective in preventing influenza virus infection and its complications, it is not as effective in the elderly due to age-associated immunosenescence phenomenon. Since 2009, a high-dose trivalen