https://www.selleckchem.com/pr....oducts/smoothened-ag
023). Age ≥40 years, ETZ and conization height are independent risk factors for margin involvement. For ages 40 years, 10 mm cone height was associated with 68.6% Negative Predictive Value (NPV) for positive margins, while for 15 mm and 25 mm, the NPV was 75.8% and 96.2%, respectively. With negative margins, the NPV for RD varied from 85.7-92.3% for up to 24 mm cone height and 100% from 25 mm. Conization 10 mm height for women 40 years provided adequate staging for almost 70%, with 10% of RD and few recurrence
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