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Accidental dislodgement of central venous catheters is a frequent complication in NICU and it often requires catheter replacement. Subcutaneously anchored sutureless devices (SAS) have been recently introduced in clinical practice for securement of different types of central catheters, but they have never been used in neonates. We evaluated safety and efficacy of SAS in neonates. All neonates who required central venous catheters inserted ultrasound-guided cannulation during 12 months of clinical practice in our NICU. We adopted SAS for