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GO is caused by the formation of orbital fat and extraocular muscle tissue fibrosis due to the swelling of orbital connective areas. Thus, managing extraocular muscle mass fibrosis is critical for the prognosis of GO. The aim of this study is to determine and experimentally validate crucial genes connected with GO and explore their particular prospective function components particularly on extraocular muscle fibrosis. Especially, we first created a spin mouse model, and performed RNA sequencing from the extra