https://www.selleckchem.com/pr....oducts/msdc-0160.htm
Moreover, rapamycin-metformin reduced the clinical arthritis score and the extent of histological inflammation and improved the metabolic profile in obese mice with CIA. Rapamycin-metformin enhanced the balance between T helper 17 and regulatory T cells in vitro and in vivo. CONCLUSIONS These results suggest that rapamycin-metformin is a potential therapeutic option for autoimmune arthritis.BACKGROUND Inaccurately modelled environmental exposures may have important implications for evidence-based policy targeting health promoting or h