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33, P.001), significantly increased CML risk. GSTM1 genotype individually and in combination with GSTT1 associated with superior rate of major molecular response (MMR) and event free survival (EFS) (log-rank P=.029). GSTO2-AG+GG genotype associated with significantly inferior MMR rates at 3, 6, and 12months. Also, patients with GSTO2-GG genotype showed significantly reduced EFS (log-rank P=.025). Multivariate analysis confirmed GSTM1 as a better (HR0.19, P=.029) and GSTO2-GG genotype as an independent poor prognostic factor (HR2.29,
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