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05). Both dynamic and static culture models increased the expression of VEGFR-2 and von Willebrand factor in encapsulated cells compared to 2D culture (p less then 0.05), showing enhanced functional maturation. Data showed a significant increase of vWF and reduction of apoptosis marker Caspase in the dynamic culture system (p less then 0.05). The levels of SOD and GPx were significantly increased in dynamic and static culture models as compared to the control 2D group (p less then 0.05). In vitro tubulogenesis assay showed significant i