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Evidence regarding the effects of ambient air pollution on new stage 1 hypertension defined by the 2017 ACC/AHA Hypertension Guideline remains sparse. To investigate the association of long-term exposure to ambient PM with stage 1 hypertension and to explore the mediating and modifying effects of PM on cardiovascular disease (CVD). A total of 32,135 participants aged 18-80 years were recruited in 2017. The three-year (2014-2016) average PM concentrations were assessed by a spatial statistical model. Blood pressure (BP) was divided into f