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Powered hand exoskeletons are an emerging technology that have shown promise in assisting individuals with impaired hand function. A number of hand exoskeleton designs have been described in the literature; however, the majority have not been supported by patient-oriented criteria. The aim of this study was to define preliminary end-user needs and expectations for an assistive hand exoskeleton. Explorative interview and case series. Six clinicians and eight individuals with impaired hand function were interviewed in small groups or ind