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A Cancer of the Liver Italian Program (CLIP) score of 0-2 (hazard ratio [HR] 3.717, P = .004) and grade 1-2 immune-related adverse events (irAEs, HR 2.217, P = .049) were predictors of overall survival (OS) in the entire cohort, and a CLIP score of 0-2 (HR 3.257, P = .009) was a predictor of OS in evaluable patients. IrAEs ≥ grade 3 were noted in 14 patients, and three died as a result. Having a single tumor and AFP response were predictors of OR, and CLIP score was a predictor of OS.The cell surface protein TMPRSS2 (transmembrane protea