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Policymakers should take the pre-established partnerships of healthcare organizations into account before delineating the area in which regionalization is meant to take place. A better alignment of governance and accountability structures is also needed for regionalization to occur in healthcare. This paper combines insights from valuation studies with sociogeographical literature and provides a framework for understanding the assembling and disassembling of "regions". This paper combines insights from valuation studies with sociogeographical literature and