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In this research, we elucidated the differential expression design of messenger RNAs (mRNAs) and circular RNAs (circRNAs) in C2S-treated MSCs and their particular involvement in the osteogenesis procedure. C2S robustly improved the osteogenic differentiation of MSCs and cranial bone defect healing. C2S-treatment modulated the differential phrase of mRNAs and circRNAs in MSCs. Differentially expressed circRNAs and mRNAs were involved in contending endogenous RNA (ceRNA-interaction companies). These ceRNA
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