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9, 17.6, and 19.7 mg kg-1 dry weight for eggs, muscle, and whole-body tissue, respectively. Collectively, these data indicate that Arctic grayling are relatively insensitive to maternally transferred Se compared to other fish species. Environ Toxicol Chem 2021;40380-389. © 2020 SETAC.The opioid crisis in the USA has resulted in over 702,000 overdose fatalities between 1999 and 2017 and can be attributed to over-prescription of opioids and abuse of synthetic opioids in combination with other illicit drugs. A rapid and sensiti