https://www.selleckchem.com/pr....oducts/sbi-0640756.h
of tyrosine and valine but did not affect eCBs or non-eCB lipids. Overall results demonstrate that 3 months of Tat exposure increased morphine tolerance and potentially innate immune tolerance evidenced by reductions in specific cytokines (e.g., IL-1α, IL-12p4 and microglial reactivity. In contrast, short-term, escalating morphine exposure acted as a secondary stressor revealing an allostatic shift in CNS baseline inflammatory responsiveness from sustained Tat exposure. Overall results demonstrate that 3 months of Tat exposure inc
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