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RIE is rare and likely secondary to a dental portal of entry or cutaneous inoculation in IVDU. Its prognosis seems to be favorable. High-risk isolation units (HRIU) house patients at high risk of transmitting infectious agents, notably patients with suspected viral hemorrhagic fever or smear-positive tuberculosis. Admission to HRIU can alter the quality of care and impact patients' and healthcare workers' (HCWs) anxiety and dissatisfaction. The Infectious Diseases Department of the Bichat Claude Bernard Hospital in Paris houses a 7-bed H