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Treatment outcomes for PTSD with current psychological therapies are poor, with very few patients achieving sustained symptom remission. A number of authors have identified physiological and immune disturbances in Post Traumatic Stress Disorder (PTSD) patients, but there is no unifying hypothesis that explains the myriad features of the disorder. The medical literature was reviewed over a 6-year period primarily using the medical database PUBMED. The literature contains numerous papers that have identified a range of physiological and i