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The postoperative analysis had been por1muc por2tub2, pT4a(SE)N3bM0H0P0CY0, pStage ⅢC. He underwent 6 programs of adjuvant chemotherapy with capecitabine plus oxaliplatin. Half a year following the surgery, CT showed 2 recurrent lesions a tumor behind the esophago-jejunal anastomosis and another when you look at the mesentery around the jejuno-jejunal anastomosis. Endoscopy showed intrajejunal invasion. Second-line treatment with paclitaxel and ramucirumab had been administered for 3 courses, leading to rapid development