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The physical examination should check for local (myofascial trigger points) and generalized signs of hyperalgesia and allodynia indicating central sensitization. In cases of endometriosis with COPCs repeated surgery for pain relief should be avoided. Amitriptyline and duloxetine can be considered as pharmacological treatment options. Pain physicians can play arole in the management of patients with endometriosis and COPCs. Amultimodal therapy should include physiotherapy and pain-related psychological treatment and possibly centrally ac
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