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A single bout of gait instruction, be it conducted on a treadmill with BWS or using a walker without BWS, is not able to alter BDNF levels and histone acetylation status in SCI clients. Nonetheless, these trials can modulate oxidative stress parameters, seemingly in a protocol-dependent manner.Multiple sclerosis (MS) is a chronic illness of the central nervous system, described as demyelinization and axonal reduction resulting, in 66% of cases, in upper limb motor impairment. The effec