https://www.selleckchem.com/pr....oducts/cloperastine-
Objective The suggested link between major depression disorder (MDD) and blood-brain barrier (BB alterations supports an impact on the neurovascular unit in this disease condition. Here we investigate how pericytes, a major component in the neurovascular unit, respond to stress, stress hormones, proinflammatory cytokine and depression.Method Hippocampal sections of chronic unpredictable stressed (CMS) rats, MDD patients and respective controls were immuno-stained against NG2, where the number of NG2+ pericytes in the m
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