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The results of this research show the necessity of introducing differential diagnostics for HPABH4 into neonatal screening practice.Binary Generalized Linear Mixed Model (GLMM) is the most common method used by researchers to analyze clustered binary data in biological and social sciences. The traditional approach to GLMMs causes substantial bias in estimates due to steady shape of logistic and normal distribution assumptions thereby resulting into wrong and misleading decisions. This study brings forward an approach governed by skew g
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