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The study aim was to analyse the frequency of polymorphic variants of angiotensinogen gene polymorphism (AGT 704TC, rs699) in essential arterial hypertension (EAH) patients. Seventy-two individuals with EAH and hypertension‑mediated organ damage (stage 2), moderate, high or very high cardiovascular risks were involved in the case-control study. Among them, 70.84 % (51) were females and 29.16 % (21) were males; mean age was 59.87±7.98 y. The control group consisted of fifty practically healthy individuals at relevant age (49.13±6.28 y)