https://www.selleckchem.com/pr....oducts/bms-927711.ht
There were 53 (83%) grade 1 and 11 grade 2 adverse events with no grade 3 or 4 adverse event. In multivariable analysis, the risk of adverse events was higher in contacts prescribed ethionamide as compared to ethambutol adjusting for age, sex and BMI (aHR 2.1 [95% CI 1.2-3.6]). Overall, there was no notable difference in treatment completion amongst the contacts who experienced an adverse event and those who did not (cOR 1.1 [95% CI 0.52-2.5]). CONCLUSION A fluoroquinolone-based preventive treatment regimen for DR-TB exposure is well