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However, because of the high misdetection rate, more in-depth learning datasets are needed for the detection of embolism below grade 3. The computer-aided diagnostic method proposed in this paper can effectively improve the detection rate of PE, especially for the detection of intra-arterial embolism above grade 3. However, because of the high misdetection rate, more in-depth learning datasets are needed for the detection of embolism below grade 3. R-spondin 1 (Rspol) and Slit2 have been found to play a vital role in cancer development