https://vs-6063inhibitor.com/p....utting-the-idea-in-t
A far more reliable indication of TICs can include the appearance of embryonic transcription factors that help lasting self-renewal, multipotency, and quiescence. We hypothesize that SOX2, OCT4, and NANOG would be enriched in ovarian TICs and will indicate TICs with high relapse potential. We evaluated a panel of eight ovarian disease cellular lines grown in standard 2-D culture or perhaps in spheroid-enriching 3-D culture, and correlated appearance with growth faculties, TIC marker expression, and chemotherapy res
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