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ADHD Treatment For Adults - Stimulant Medication Stimulant medicines like methylphenidate or dextroamphetamine are generally considered as the first line treatment for adults with ADHD. These drugs increase and balance neurotransmitters, which are brain chemicals. Non-stimulant medications like antidepressants and atomoxetine can be prescribed when stimulants are not appropriate for the patient because of other health problems or side effects. The