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The technique is better able to pinpoint the placement of the ligand binding website than a comparable pocket detection algorithm (Pocket-Finder) on a dataset of 134 proteins. One of the strengths of the strategy is its prediction of relatively small websites. The sites have volumes roughly equivalent to ligand volumes regardless of the general measurement of the protein. This is in distinction to pocket detection, where predicted site volumes present a much larger tendency to increase with protein measurement. This property would appear to be a results of usin
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