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The proposed sensor also possessed good reproducibility, repeatability, long-term stability, selectivity, and satisfactory recovery in serum samples analysis. Therefore, it has the great potential for the accurate quantification of DA and AC in complex matrixes.The development of rapid, highly sensitive, and selective methods for the diagnosis of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) should help to prevent the spread of this pandemic virus. In this study, we combined recombinase polymerase amplificat