https://www.selleckchem.com/pr....oducts/mi-773-sar405
In CL patients with molecular evidence of Leishmania persistence in the NM, genes characteristic of an anti-inflammatory and tissue repair responses (IL4R, IL5RA, POSTN and SATB1) were over-expressed relative to NM samples from CL patients in which Leishmania was not detected. Here, we report the first immunological description of subclinically infected NM tissues of CL patients, and provide evidence of a local anti-inflammatory environment favoring parasite persistence in the NM. Copyright © 2020 American Society for Microbiol