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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD find their symptoms improve by taking medication. Every person's reaction is different, and side effects can be a problem. Methylphenidate is part of a class of drugs referred to as stimulants. It increases the levels of a chemical in the brain that helps regulate behavior and attention. Stimulant drugs Stimulants enhance attention and concentration in 70% to the 80% of adults and children who use