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Because MALT1 remains understudied in this framework, we sought to investigate how MALT1 proteolytic activity plays a part in the entire allergic reaction. We contrasted bone tissue marrow-derived mast cells from MALT1 knockout (MALT1-/-) and MALT1 protease-deficient (MALTPD/PD) mice to wild-type cells. We unearthed that MALT1-/- and MALT1PD/PD mast cells are similarly damaged in cytokine manufacturing following FcεRI stimulation, indicating that MALT1 scaffolding ac
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